Количество страниц: 6 с.
Time to the most recent common ancestor (TMRCA) of Sakha men with haplogroup N3a2-M1982 of the Y chromosome was evaluated by 23 STR markers using the mutation rate constant of Y-STR loci that we had previously calculated. The obtained TMRCA values indicate a period of ~1300-1400 years ago (VI-VII centuries AD), associated with the primary expansion of the population. Based on genetic data and analysis of texts from ancient Chinese chronicles, a hypothesis has been put forward about the connection of the ancestral Sakha population with the Yuzhe people, who supplied mammoth ivory to China.
Адамов, Д. С. Датировка времени ближайшего общего предка саха (якутов) с гаплогруппой N3A2-M1982 Y-хромосомы: новые этногенетические реконструкции / Д. С. Адамов, А. Н. Алексеев, С. А. Федорова ; Якутский научный центр комплексных медицинских проблем, Северо-Восточного федерального университета им. М. К. Аммосова, Институт естественных наук, Институт гуманитарных исследований и проблем малочисленных народов Севера // Якутский медицинский журнал. - 2024. - N 2 (86). - С. 88-93. - DOI: 10.25789/YMJ.2024.86.21
DOI: 10.25789/YMJ.2024.86.21
Количество страниц: 4 с.
- Математика. Естественные науки > Общая биология. Антропология. Вирусология. Микробиология,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина,
- НАУКА ЯКУТИИ > МАТЕМАТИКА. ЕСТЕСТВЕННЫЕ НАУКИ > Общая биология. Антропология. Вирусология. Микробиология,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина.
The study is devoted to studying the relationship between the rs9939609 polymorphism of the FTO gene and body mass index (BMI) in the Yakut population. The sample consisted of 521 participants of Yakut nationality without diabetes mellitus. An analysis of the distribution of frequencies of occurrence of alleles and genotypes was carried out, as well as an analysis of BMI indicators in groups with different genotypes of the rs9939609 polymorphism of the FTO gene, during which similarities were found in the ratios of allele frequencies with populations of East and South Asia. The study showed a weak association of obesity with the risk allele A when comparing the group with normal BMI and the combined group of obesity + pre-obesity.
Бочуров, А. А. Ассоциация полиморфизма rs9939609 гена FTO с индексом массы тела в популяции якутов / А. А. Бочуров, Н. И. Павлова, А. В. Крылов, С. К. Кононова ; Якутский научный центр комплексных медицинских проблем // Якутский медицинский журнал. - 2024. - N 2 (86). - С. 35-38. - DOI: 10.25789/YMJ.2024.86.08
DOI: 10.25789/YMJ.2024.86.08
Количество страниц: 4 с.
- Математика. Естественные науки > Общая биология. Антропология. Вирусология. Микробиология,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Патология. Клиническая медицина > Онкология,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Патология. Клиническая медицина > Онкология,
- НАУКА ЯКУТИИ > МАТЕМАТИКА. ЕСТЕСТВЕННЫЕ НАУКИ > Общая биология. Антропология. Вирусология. Микробиология.
The evaluation of the status of lipid peroxidation and the glutathione system in patients with lung cancer depending on the histological form and stage of the disease has been carried out. The intensity of free radical oxidation of lipids was assessed by the accumulation of malondialdehyde. The indicators of the glutathione system were assessed by the concentration of the reduced form of glutathione and the activity of enzymes: glutathione peroxidase, glutathione reductase, glutathione transferase. Our data indicate that as the clinical stage of lung cancer develops, the level of lipid peroxidation increases, against the background of inhibition of the glutathione reductase activity). Higher levels of malondialdehyde in patients with adenocarcinoma suggest that tumor development may be more closely related to oxidative stress.
Румянцев, Е. К. Уровень показателей системы глутатиона и перекисного окисления липидов в крови больных раком легкого / Е. К. Румянцев, Е. В. Томтосова, В. М. Николаев ; Якутский научный центр комплексных медицинских проблем // Якутский медицинский журнал. - 2024. - N 2 (86). - С. 31-34. - DOI: 10.25789/YMJ.2024.86.07
DOI: 10.25789/YMJ.2024.86.07
Количество страниц: 3 с.
- Математика. Естественные науки > Общая биология. Антропология. Вирусология. Микробиология,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Медицина > Анатомия. Физиология,
- НАУКА ЯКУТИИ > МАТЕМАТИКА. ЕСТЕСТВЕННЫЕ НАУКИ > Общая биология. Антропология. Вирусология. Микробиология,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Медицина > Анатомия. Физиология.
The role of pathogenic variants of the MY015A gene in the etiology of hearing loss has not been sufficiently studied in the world, since the larger size of the gene (66 exons, 71 kb) suggests the search for pathogenic variants using NGS technologies, which are not yet sufficiently used in routine practice. In this regard, it is relevant to study the role of pathogenic variants of the MY015A gene in the etiology of non-syndromic forms of hearing impairments The purpose of this work is to describe the rare pathogenic variant c.7636C>T p.(Gin2546*) in the MY015A gene, found in a homozygous state in two siblings with prelingual profound sensorineural hearing loss from a Buryat family. Previously, this variant was found only in one patient in a compound-heterozygous state with another nonsense variant in the MY015A gene in Brazil and described as pathogenic. Detection of variant c.7636C>T p.(Gln2546*) in a homozygous state in Buryat siblings may indicate either a rare case of endogamous marriage or a wider distribution of this variant in the Lake Baikal region.
Редкий вариант с.7636С>Т р.(С1п2546*) гена MY015A у двоих пациентов из Бурятии ссенсоневральной глухотой / A. M. Чердонова, Т. В. Борисова, Ф.М. Терютин, B. Г. Пшенникова, А. В. Соловьев, Г.П. Романов, C. А. Федорова, Н. А. Барашков // Якутский медицинский журнал. - 2024. - N 1 (85). - С. 27-29. - DOI: 10.25789/ҮШ.2024.85.07
DOI: 10.25789/ҮШ.2024.85.07
Количество страниц: 8 с.
- Математика. Естественные науки > Астрономия. Астрофизика. Исследование космического пространства. Геодезия,
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Управление предприятиями. Организация производства, торговли и транспорта,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Управление предприятиями. Организация производства, торговли и транспорта,
- НАУКА ЯКУТИИ > МАТЕМАТИКА. ЕСТЕСТВЕННЫЕ НАУКИ > Астрономия. Астрофизика. Исследование космического пространства. Геодезия.
A spatial analysis of intra-regional transport accessibility of settlements in the Arctic districts of the Sakha Republic (Yakutia) by GIS is an urgent task and can become a necessary support for the processes of decision-making and planning of sustainable development of these territories. The purpose of the study is to perform a spatial analysis of intra- regional transport accessibility of settlements in remote Arctic regions of Yakutia on the example of Anabarsky and Nizhnekolymsky districts. On the basis of the GIS network analysis and calculated coe cients of density of the transport network, the assessment of transport accessibility of the study areas according to winter and summer scenarios was carried out. The automobile and river networks were built on the basis of data from open cartographic sources: OpenStreetMaps and Google Earth Engine, the atlas of highways of the Sakha Republic (Yakutia). On the basis of satellite images of Landsat 5, 8 and Sentinel 2, non- o cial (informal) roads that play an important role in communications between settlements were decrypted and digitized. QGIS and ArcGIS programs were used to perform network analysis and build a map of time availability of the settlements using isochronous method. The created maps clearly show the availability of settlements by time interval. The conducted research made it possible to determine that remote sensing and geoinformation systems are key tools for a spatial analysis of transport infrastructure. Using this tools, it is possible to conduct network analysis of various levels of complexity, as well as build graphs of the transport network, greatly simplifying the counting procedure. The paper tested a method that allows to identify uno cial roads in the Arctic, and the presented methods of GIS analysis and modeling that can be used for further deeper network analytics and graph theory to improve the methodology for studying the transport accessibility of the Republic of Sakha (Yakutia).
Обутов, К. А. Пространственный анализ внутрирайонной транспортной доступности с использованием сетевого ГИС-анализа (на примере Анабарского и Нижнеколымского улусов) / К. А. Обутов, А. Н. Саввинова ; Северо-Восточный федеральный университет им. М. К. Аммосова // Вестник Северо-Восточного федерального университета им. М. К. Аммосова. Серия: Науки о земле. - 2023. - N 4 (32). - C. 111-118. - DOI: 10.25587/2587-8751-2023-4-111-118
DOI: 10.25587/2587-8751-2023-4-111-118
Количество страниц: 6 с.
- Прикладные науки. Медицина. Ветеринария. Техника. Сельское хозяйство > Инженерное дело. Техника в целом > Строительство подземных сооружений. Земляные работы,
- Математика. Естественные науки > Общая геология . Метеорология. Климатология. Историческая геология. Стратиграфия. Палеогеография,
- НАУКА ЯКУТИИ > ПРИКЛАДНЫЕ НАУКИ. МЕДИЦИНА. ТЕХНИКА. СЕЛЬСКОЕ ХОЗЯЙСТВО > Инженерное дело. Техника в целом > Строительство подземных сооружений. Земляные работы,
- НАУКА ЯКУТИИ > МАТЕМАТИКА. ЕСТЕСТВЕННЫЕ НАУКИ > Геология. Геологические и геофизические науки.
The large amount of peaty soils on the territory of the Russian Federation, especially in the Arctic zone, necessitates the study of their temperature regime and thermophysical properties. The paper presents the results of an experimental study of the thermal conductivity and amount of unfrozen water in sandy soils with varying degrees of peat content. Experiments were carried out on samples with a damaged structure, which were represented by slightly decomposed peat, medium-grained river sand and their various mixtures. It has been established that the degree of peat content affects such physical values as porosity, thermal conductivity and the amount of unfrozen water. For thawed peaty sandy soils, as the degree of peat content increases, the porosity value increases. For both thawed and frozen peaty sand soils, thermal conductivity decreases with increasing degree of peat content. Moreover, the thermal conductivity for frozen soils are higher than for thawed soils. The amount of unfrozen water also depends on the degree of peat in the soil and decreases as it increases. The measured thermophysical properties of peaty sand soil can be used to model the temperature regime in the area of frozen and thawed peat soils.
Теплофизические свойства торфов и заторфованных песчаных грунтов / Протодьяконова Н. А., Степанов А. В., Тимофеев А. М. [и др.] ; Институт физико-технических проблем Севера им. В. П. Ларионова // Успехи современного естествознания. - 2024. - N 1. - С. 52-57. - DOI: 10.17513/use.38207
DOI: 10.17513/use.38207
Количество страниц: 6 с.
This article contains data on the nature and level of study of the territories in which the north-eastern part of the Sakha Republic is located, which are potentially oil and gas bearing. In 1979-1992, seismic exploration of oil and gas was carried out in the Tastakh trough, the Zyryanka depression by JSC Yakutskgeofizika. The section of the Tastakh trough includes strata of terrigenous rocks of lithological unconstrained composition. Its capacity is 2.5-4.5 kilometers. The paper describes reflecting horizons based on Neogene-Quaternary, Jurassic-Cretaceous deposits. In addition, during the research, it was found that the Lower Cretaceous sediments present in the Tompon depression are divided by the Tomporuk-Kitchan zone of thrust divisions of the Late Cretaceous stage of activation of the Verkhoyano-Kolyma region. Upper Jurassic volcanogenic sedimentary rocks, Lower Cretaceous coal-bearing deposits are contained in the Zyryanka depression at 6 and 5 thousand meters, respectively. This article contains an opportunity for the allocation of time intervals, interpretation of sedimentary synchronous complexes of deflections, depressions, shelf. Seismic materials in these territories have a quality that can be recycled. The evidence of the need for this procedure appears during discussions on the topic of geological development, the structure of the mountain-folded Verkhoyano-Kolyma region, as well as the shelf that adjoins it. These data are confirmation of the presence of oil and gas in these territories. The work was carried out with the scientific equipment of the Center for Collective Use of the Federal research center ҺYakut Scientific Center of the Siberian Branch of the Russian Academy of Sciencesһ under grant No. 13.TsKP.21.0016. Support was received in the form of funds under the State Assignment from the Ministry of Science and Higher Education of the Russian Federation No. 122011100158-1.
Оболкин, А. П. Анализ сейсморазведочных исследований для оценки нефтегазоносности северо-востока Якутии / Оболкин А. П., Слепцова М. И., Севостьянова Р. Ф. ; Институт проблем нефти и газа // Успехи современного естествознания. - 2023. - N 12. - С. 193-198. - DOI: 0.17513/use.38191
DOI: 10.17513/use.38191
Количество страниц: 8 с.
The northern slope of the Yakut uplift covers the North Aldan oil and gas bearing region and partially the Pre-Verkhoyansk and Vilyui oil and gas bearing regions. The potential oil and gas content of the Northern slope of the Yakut uplift is associated with a wide stratigraphic range of promising sediment complexes (Vendian-Cambrian, Permian-Triassic and Jurassic-Cretaceous). All these complexes have confirmed oil or gas occurrences of varying intensity. Terrigenous-carbonate formations of the Vendian-Cambrian complex are the most promising deposits in terms of oil and gas potential, confined to the lower part of the upper sub-suite of the Yudom formation of the Vendian. A relatively effective fluid seals for the Vendian hydrocarbons can be the variegated formation of the Lower Cambrian, composed of dense mudded-off carbonate rocks. The prospects of Permian-Triassic and Jurassic-Cretaceous sediment complexes will be determined by the absence or presence of zonal and local fluid seals, including non-traditional permafrost hydrate. Thus, several oil and gas complexes of different origin and with different types of fluid seals are identified in the section. A brief overview of the promising oil and gas complexes of the Northern slope of the Yakut uplift emphasizes the need for priority geological exploration for oil and gas. Clarification of geological structure of the studied area will make it possible to identify the most promising zones and sites for planning and organzing exploration work. The work was carried out with financial support within the framework of the State Assignment of the Ministry of Science and Higher Education of the Russian Federation No. 122011100158-1 using scientific equipment of the Center for Collective Use of the Federal research center "Yakut Scientific Center of the Siberian Branch of the Russian Academy of Sciences" within the framework of grant No. 13.TsKP.21.0016.
Калинин, А. И. Перспективные нефтегазоносные комплексы на северном склоне Якутского поднятия / Калинин А. И. ; Институт проблем нефти и газа // Успехи современного естествознания. - 2023. - N 12. - С. 185-192. - DOI: 10.17513/use.38190
DOI: 10.17513/use.38190
Количество страниц: 6 с.
The article is devoted to the ecological and geographical assessment of the territory of the republican resource reserve ҺTuostakhһ for tourist and recreational activities, which is located in the Verkhoyansk ulus of the Republic of Sakha (Yakutia) in the river basin. Tuostakh, on an area of 503530.0 hectares. Organized in 1997. During the study of the reserve, a comprehensive analysis of the natural, geomorphological, climatic, plant, animal and other features of the resource reserve was carried out. The regime of use of the reserve is considered, in particular the prohibited and permitted types of activities on their territory. It has been established that tourism activities are partly prohibited, which contradicts visiting the unique natural monuments located in this reserve, and in permitted activities, for example, gathering and fishing are permissible only for the local population, which in some way loses the tourist attractiveness of this area of nature, especially rich in berries, mushrooms and fish. The criteria for environmental sustainability of the reserve’s landscapes were assessed. The overall assessment of environmental sustainability was 9 points, which corresponds to environmentally unsustainable landscapes of protected areas. As a result of the research and assessments, some conclusions were developed on the territorial planning arrangement of the resource reserve, functional zones and their regimes, as well as on the joint coordinated work of state environmental authorities with tourism companies, which are currently operating on the territory of the resource reserve not agreed upon and not organized. Some recommendations are given when planning tourism in this unique area of nature.
Николаев, А. А. Эколого-географическая оценка ресурсного резервата "Туостах" для туристско-рекреационной деятельности / Николаев А. А. ; Северо-Восточный федеральный университет им. М. К. Аммосова // Успехи современного естествознания. - 2023. - N 12. - С. 140-145. - DOI: 10.17513/use.38184
DOI: 10.17513/use.38184
Количество страниц: 6 с.
The article considers the supporting framework of the territory as the basis for the sustainable development of tourism in specially protected natural areas. The study presents the results of the analysis of scientific literature on the topic under study. During the processing of theoretical materials, the main elements of the supporting framework of the territory were identified. These elements formed the basis for the formation of a single framework of the Belyanka resource reserve (Belyanka RR). The obtained results of field research conducted in the period from 2022 to 2023 became the basis for writing the article. Statistical data on visits to the Belyanka region over the past 6 years were processed, according to the results of which the main goals of visiting the reserve were identified. 3 areas have been identified according to the target areas of economic activity carried out in the visited territories. The main elements of the framework are grouped according to the importance of their influence on the development of the designated areas of the specially protected natural territory of Belyanka. In addition, the article presents the results of the inventory of tourist and recreational resources of the Belyanka region. Thus, the resources were divided into the following groups: objects located in the zone of absolute rest; objects of the zone of traditional nature management; objects of the Lena part and the mountainous part located outside the boundaries of the specially protected natural territory of Belyanka. As a result of the conducted desk and field research, a cartographic diagram of the Belyanka district with a single supporting frame of the Belyanka district territory was compiled.
Егоров, С. С. Определение туристского опорного каркаса особо охраняемой природной территории "Белянка" / Егоров С. С. ; Северо-Восточный федеральный университет им. М. К. Аммосова // Успехи современного естествознания. - 2023. - N 11. - С. 77-82. - DOI: 10.17513/use.38174
DOI: 10.17513/use.38174